Raducanu, who reached the fourth round in California last year, lost 6-3 7-5 to two-time major winner Sabalenka as she continues her comeback.
The 21-year-old, ranked 250 in the world, was a wildcard at the tournament following an injury-disrupted 2023.
“It was a good success, I would say,” Raducanu said of her week.
“I think I have handled myself a lot better on the match court. I was a lot more positive and hungry to play, and that showed I think in the tennis that I did play.”
Raducanu’s second-round victory over Dayana Yastremska, who retired with illness, was the first time the English player had recorded back-to-back wins since successfully coming through three in a row at Indian Wells 12 months ago.
The shock 2021 US Open champion made her return to the tour in January following an eight-month absence, during which she had operations on both of her wrists and surgery on her ankle.